caspofungin

2024-05-15


Mechanism of Action: Caspofungin, a semisynthetic echinocandin antifungal, shows activity against Aspergillus and Candida species. It inhibits the synthesis of β-1,3-D-glucan, an essential component of the fungal cell wall that is not present in mammalian cells.

Caspofungin is an antifungal drug for the treatment of invasive aspergillosis and invasive candidiasis in neutropenic patients. Learn about its indications, dose, interactions, side-effects, pregnancy, breast feeding and hepatic impairment.

It is most likely that FITC-caspofungin accumulated at the cell membrane, since the target of caspofungin is β-1,3-d-glucan synthase, an integral protein of the cell membrane.

Expert opinion. Caspofungin is a semisynthetic derivative from pneumocandin B and the first member of the echinocandins that was approved by the U.S. Food and Drug Administration (FDA) to fight fungal infection. Caspofungin inhibits the enzyme β (1,3)-D-glucan synthase of the fungal cell wall resulted in inhibition of the synthesis of β ...

Rezafungin, a new US Food and Drug Administration-approved, long-acting echinocandin to treat candidaemia and invasive candidiasis, was efficacious with a similar safety profile to caspofungin in clinical trials. We conducted pooled analyses of the phase 2 STRIVE and phase 3 ReSTORE rezafungin trials.

Caspofungin is an antifungal medicine given by injection to treat serious fungal infections, such as candidemia, esophageal candidiasis, and aspergillosis. Learn about its brand name, precautions, and how to use it safely.

Caspofungin is a lipopeptide that disrupts the cell wall of yeasts and filamentous fungi, including aspergillosis and candidiasis. It is effective in vivo and in vitro against a number of other fungal species and has a good safety profile. Learn about its mechanism of action, clinical applications, and combination strategies.

Detailed Caspofungin dosage information for adults and children. Includes dosages for Candidemia, Esophageal Candidiasis, Aspergillosis - Invasive and more; plus renal, liver and dialysis adjustments.

Caspofungin (INN; brand name Cancidas) is a lipopeptide antifungal drug from Merck & Co., Inc. discovered by James Balkovec, Regina Black and Frances A. Bouffard. It is a member of a new class of antifungals termed the echinocandins.

Caspofungin adalah obat golongan kelas anti-jamur yang disebut echinocandin semisintetik ( semisynthetic echinocandin ). Obat ini digunakan untuk mencegah berbagai infeksi karena jamur. [1,2,3] Penjelasan terkait, perhatikan tabel berikut ini; [1] Indikasi. Obat anti-jamur.

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